Sports September 17, 2026 at 10:39 PM

'Thursday Night Football' prediction, odds, spread, time: Lions vs. Bills picks from expert on 22-11 roll

CBS Sports

Larry Hartstein reveals his picks for Detroit Lions vs. Buffalo Bills in the 2026 Week 2 'Thursday Night Football' matchup

SportsLine's Machine Learning Model AI reveals its NFL SGP for Lions vs. Bills on 'Thursday Night Football'

SportsLine's model has analyzed the Week 2 NFL schedule and locked in its Week 2 NFL picks, predictions

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